Senior Scientist, Ophthalmology

Switzerland, Basel-City, Basel Headquarter

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• Job facts

Senior Scientist, OphthalmologyThe Neuroscience, Ophthalmology and Rare Diseases (NORD) Translational Area (DTA) of Roche Pharmaceutical Research & Early Development (pRED) has an opening for a Scientist within the Ophthalmology department located in Basel, Switzerland.  This group of Roche scientists is focused on the clinical translation of therapeutic approaches for eye diseases, including age related macular degeneration, diabetic retinopathy, and glaucoma.We are seeking an exceptional, highly motivated, and talented Scientist to perform
in vivo experiments testing novel drug candidates using established and emerging animal models of ocular diseases.  As a Scientist, you will interact closely with other scientists, postdoctoral fellows, and other associates, in a laboratory focused on the development of new therapeutics for ocular diseases using in vivo models. You will hold several of these primary responsibilities:

• Perform animal procedures, including ocular (intravitreal, subconunctival, anterior chamber, subretinal, suprachoroidal) and intravenous injections, anesthesia, ocular surgeries (vitreous and aqueous sampling)


• Perform in vivo retinal imaging of animal models under anesthesia using scanning laser ophthalmoscopy and/or optical coherence tomography (using Heidelberg Spectralis and/or Micron IV imaging systems)


• Perform ocular and non-ocular tissue dissections with subsequent sample preparation for downstream analyses (histopathology, microscopy, proteomics, RNA-seq).


• Isolate cells from animal models of eye disease, and maintain primary cell cultures and cell lines


• Perform electroretinography (ERG) and optokinetic tracking (OKT) analysis of animal models of ocular disease

You hold a PhD, D.V.M., and/or MD, and have 5 or more years’ research experience involving animal models of ocular disease.Furthermore, you will bring the following skills and qualifications:

• You have a track record of hands-on experience with animal handling and procedures, including injections, in vivo imaging, anesthesia, and survival surgeries


• Experience directly performing mechanistic studies using in vivo ocular disease models


• A strong track record of publications in the field of ophthalmology or related fields, including immunology and vascular biology


• Fluency in English communication skills are required and German language proficiency is highly desirable

Get in touch with the Recruiting Team Switzerland +41 61 68 225 50

 

At Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity

Roche is an equal opportunity employer.

Research & Development, Research & Development > ResearchBasel Headquarter

• Who we areAt Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
  
  Roche is an equal opportunity employer.


• Job facts
  
  
  
  • Location Switzerland, Basel-City, Basel Headquarter
  
  
  • Function Research & Development
  
  
  • Subfunction Research
  
  
  • Schedule Full time
  
  
  • Job level Individual contributor
  
  
  • Job type Regular
  
  
  • Division Roche Pharmaceuticals
  
  
  • Posted since 2018/05/08
  
  
  • Job-ID 3246877001
  
  


• Get in touchMrs. Mélodie Lee Mairon


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