At Lonza, we invest in great people. We encourage our employees to challenge themselves and we offer an environment that fosters creativity and success. Headquartered in Basel, Switzerland, we operate production, R&D, and business sites around the world, including Europe, North America, and Asia.
We strive to be the leading supplier using science and technology to improve the quality of life.
We work with passion, using advanced technologies, to transform life science into new possibilities for our customers.
For DPS (Drug Product Services) in Basel Switzerland, we have an open position for a Lead Scientist in our growing Formulation Development team. Working closely with Analytical Development and Formulation Development, this team offers specialized services solutions for customers. Become part of this exciting opportunity by applying for the position of Lead Scientist Formulation Development.
Key responsibilities
Help establishing Drug Product formulation development infrastructure and services for parenteral drug products for clinical and commercial use
Install, qualify, and maintain equipment for formulation/process development, non-GMP manufacturing and analytics in close alignment with current best practices and regulations
Plan and perform formulation and process development studies for liquid and lyophilized parenteral drug products of biologics (e.g. monoclonal antibodies, novel formats, ADCs, peptides), peptides and small molecules
Document data following applicable lab procedures and current documentation practices. Evaluate results and summarize in short reports
Execute analytical tests to support formulation and process development (e.g. HPLC and CE purity methods, content by UV, identity, color, clarity and opalescence, pH, osmolality, visible particles, subvisible particles).
Ensure safety and health protection following lab and safety instructions
Evaluate and implement new methods and technologies, as required. Contribute to innovation, technical strategy projects and scientific publications
Manufacture non-GMP drug product samples for supportive stability studies and preclinical use (e.g. GLP tox studies) applying aseptic working techniques
Perform other duties as assigned.
Qualification :
A science or engineering degree (BSc, MSc) in a relevant discipline, e.g. Pharmaceutical Sciences, Biochemistry, Biology, Biochemical Engineering or a training on the job as lab technician
Experience
>8 years of experience as a research/technical assistant in the pharmaceutical or chemical industry, preferably in the pharmaceutical development
Good working experience in relevant pharmaceutical development and analytical technologies
Experience with parenteral dosage forms, protein formulation and analytics and aseptic working techniques