Digital Biomarker Science and Study Lead: Multiple Sclerosis

Switzerland, Basel-City, Basel Headquarter

defresrutritptzhja

Apply now!Print

• Job facts

Who We Are

At Roche, over 90,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche's Pharma Research and Early Development Informatics team is the bridge between digital technology and science. We help drive medical innovation and are integral to the realisation of truly Personalised Healthcare and the development of innovative treatments for our patients.

Digital tools, such as smartphones or wearables, can now continually measure and collect vital health information – or “Digital Biomarkers” – from Multiple Sclerosis (MS) patients. Digital Biomarkers are changing how future medicines will be developed and could lead to more personalised use of new medications that will transform the lives of MS patients. Advances in wearable devices, such as phones, watches, textiles or delivery devices, which track a patient’s vital signs and monitor for symptoms, all have the potential to vastly accelerate clinical development.

Roche is dedicated to creating community- and regulator-accepted endpoints and outcomes that will redefine the measurement of MS disease progression, and thereby change the understanding of MS as a disease. We’re seeking future-thinking innovators who know how to apply their expertise to help transform MS.

The Position

As a Digital Biomarker Science and Study Lead for MS you will:

• collaborate with clinical development teams, scientists, and physicians to plan and design remote patient monitoring (RPM) concepts based on the newest scientific literature and available data and implementation into our clinical trials


• define key excellent scientific and clinical hypotheses for the RPM data analysis to address, and supervise quality of results to ensure significant conclusions can be drawn that impact decision-making


• drive Digital Biomarker collaborations with external organizations, e.g. with hospital networks, payers, and industry consortia


• drive the Digital Biomarker scientific publication strategy, including scientific peer reviewed journals and conferences, including specialized journals/conferences in the therapeutic area of interest, machine learning and digital medicine journals/conferences, and in Neuroscience more broadly


• exercise your judgement to ensure RPM solutions are implemented, integrated or sourced to most effectively meet the needs of the programs


• design and execute qualitative studies, including physician and patient focus groups, to establish clinical meaningfulness of the collected data and optimize the usability of software/remote patient monitoring solutions


• develop remote patient monitoring aspects of the clinical trial design, protocols and informed consents


• project manage the deployment of the remote patient monitoring solutions into clinical studies


• deliver trainings on the remote patient monitoring approach to physicians and study coordinators


• present digital biomarker data analysis results to internal decision bodies and external expert audiences, build trust and gain support for this new data type


• manage internal and external stakeholders

Who You Are

You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point. If you bring the following qualifications, we are looking forward to your application:

• real passion for transforming healthcare using digital technology, and especially for using these novel technologies to modernize clinical endpoints in drug development and improve disease management and patient care


• very good university degree (PhD. level) in cognitive science, neuroscience, biomedical engineering or a related medical or natural science discipline and an excellent publication record in neuroscience and related areas


• extensive experience in Multiple Sclerosis clinical research with previous experience in experimental/clinical study design


• experience in the pharmaceutical or related industry, ideally with direct involvement in clinical development and in a role with a scientific component


• excellent analytical, communication and presentation skills


• experience with software development projects, and especially with functional requirement models like use case and user story development, and requirement gathering


• self-starting teammate


• problem solving attitude and structured approach to work in complex fast changing environments


• data driven mindset


• native English

Should you have these additional nice-to-have skills, you are the ideal team member we are searching for:

• previous experience in working directly with patients


• previous clinical experience in Parkinson’s Disease, Autism Spectrum Disorder, Schizophrenia, neuromuscular atrophies/dystrophies


• previous experience with analyzing data and/or implementation of information workflows

If you are proud of contributing and feel you have the dedication to teamwork and innovation that we are seeking, then Roche is the organization for you. Every role at Roche plays a part in making a difference to patients’ lives. If you want work in a passionate team, make your mark & improve lives, apply now.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

If you have questions, please check our FAQs and videos on careers.roche.ch/faq.

Helpful links illustrating recent work in our Digital Biomarker Programme team:

Multiple Sclerosis:

www.youtube.com/watch?v=Bqu64uBEE2c&feature=youtu.be

floodlightopen.com

www.btcalgary.ca/video/iframe/2226196965001/SkX1bBGY/5838106745001

www.roche.com/de/media/releases/med-cor-2018-10-02.htm

www.futuremedicine.com/doi/pdf/10.2217/nmt-2017-0054

www.roche.com/media/store/releases/med-cor-2017-10-27.htm

www.youtube.com/watch?v=6BPS5tl2RRc

www.youtube.com/watch?v=k8XulS3IxBc

Roche Digital Biomarker programme overview:

isctm.org/public_access/Autumn2018/Presentation/Gossens-Aut18.pdf

Parkinson’s Disease:

onlinelibrary.wiley.com/doi/full/10.1002/mds.27376

Huntington’s Disease:

curehd.blogspot.com/2018/03/roche-gears-up-for-pivotal-phase-3.html

medically.roche.com/en/search/pdfviewer.e2f056a3-8a05-4b97-9dc1-f816505c30ca.html

Schizophrenia:

isctm.org/public_access/Autumn2018/PDFs/Umbricht-Poster.pdf

• Who we areAt Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
  
  Roche is an equal opportunity employer.


• Job facts
  
  
  
  • Location Switzerland, Basel-City, Basel Headquarter
  
  
  • Function Research & Development
  
  
  • Subfunction Research Informatics
  
  
  • Schedule Full time
  
  
  • Job level Individual contributor
  
  
  • Job type Regular
  
  
  • Division Roche Pharmaceuticals
  
  
  • Posted since 2019/01/30
  
  
  • Job-ID 201901-102758
  
  


• Get in touchMs. Nicole Gampp


• You could also like these jobs

  Digital Biomarker Data Analysis Lead: Multiple Sclerosis

  Switzerland, Basel-City, Basel Headquarter

  Software Architect for Lab Data Automation in Pharma Research (m/f)

  Switzerland, Basel-City, Basel Headquarter

  Digital Biomarker Science and Study Lead: Multiple Sclerosis

  Switzerland, Basel-City, Basel Headquarter

Apply now!