Job Detail

We are offering a unique opportunity to join our team in the Roche Innovation Center Basel.

Preclinical Chemistry, Manufacturing and Controls is a global function within Pharma Research and Early Development (pRED). We develop robust and innovative API synthesis and drug products to supply and enable key preclinical activities paving the way towards Entry Into Human. We are CMC experts and together with our discovery functions partners, we generate scientific and technical knowledge to assess the developability of drug candidates. We build our strength on a broad diversity of enthusiastic technical experts, pharmacists, chemists and analytical scientists delivering and innovating in the space of small molecules, peptides and oligonucleotides.

In this role:

• You will be part of a team of pharmacists, chemists, biophysical and analytical sciences experts, supporting a diverse portfolio of small molecule, peptides and nucleic acid discovery projects. You are responsible for the physico-chemical characterization of drug molecules and evaluation of the developability of new molecules to transform them into a medicine. You will design formulation concepts suitable for preclinical and toxicological programs as well as support the establishment of Entry into Human formulation strategies. This includes the investigation, evaluation and implementation of innovative drug delivery and targeting technologies to meet the target product profile of new drugcandidates. You are accountable for the scientific and technical excellence of the work performed within your area of responsibility


• You stay abreast of developments and trends pertinent to preformulation, pharmaceutical technology, drug delivery and targeting of small molecules, peptides and nucleic acids. You attend relevant conferences, build strong internal and external relationships to maintain a strategic understanding of the drug R&D technology environment and recommend priorities


• You are committed to performing lab work


• As a pCMC (deputy) Project Leader, you orchestrate all preclinical CMC activities (internal and external) and ensure an efficient project transfer to Pharmaceutical and Analytical Development to proceed to clinical studies


• You may participate in the assessment of business development opportunities

What else are we offering?

We are dedicated to support our staff in the development of their knowledge and skills and offer further career opportunities where people demonstrate talent and aptitude.

Who are we looking for?

We are seeking a committed individual who brings:

• PhD in Pharmaceutical Technology, Biopharmaceutics, Biophysics or similar field with Postdoc and 2-5 years of experience in the formulation R&D space


• You possess a sound understanding of the drug development process and a deep knowledge of key aspects and scientific methods used to design and develop formulation for drug candidates


• Expertise in oral and parenteral dosage forms


• Expertise in drug delivery (e.g. to the brain), drug targeting, nano-technology, cell culture and a deep understanding of biological barriers is a key asset


• Expertise in data workflows and/or prediction of physico-chemical properties is an advantage


• Creative thinking. You are curious or passionate about scientific and technical innovation. You can quickly learn and adapt your thinking to complex and evolving environments


• Ability to guide the work of others and operate in agile teams. You can lead and motivate others, as well as prioritize and coordinate their work through to successful outcomes


• Strong cross-functional teaming skills: you have an inclusive and collaborative way of interacting. You demonstrate good communication skills that enable you to effectively collaborate within cross-functional teams (Discovery and Technical Development Teams) and interact across interfaces (Toxicology, DMPK, Discovery Biology, Therapeutic Modalities, Regulatory and Clinical Development)


• Fluency in English; good command of German is of advantage

Are you ready to apply?