Job Detail

Research Associate, Formulation Development (small molecule parenterals)

Inseriert am: 17.02.2020
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At Lonza, we invest in great people. We encourage our employees to challenge themselves and we offer an environment that fosters creativity and success. Headquartered in Basel, Switzerland, we operate production, R&D, and business sites around the world, including Europe, North America, and Asia. 


Our vision:


We strive to be the leading supplier using science and technology to improve the quality of life.


Our mission:


We work with passion, using advanced technologies, to transform life science into new possibilities for our customers.
 


Do you want to help us as we shape the future of this great organization?


 


Job Description Summary


For DPS (Drug Product Services) in Basel Switzerland, we have an open opportunity for a Research Associate. Working closely with Analytical and Formulation Development, this team offers specialized services solutions for customers. Become part of this exciting opportunity by applying for the position of Research Associate Formulation Development.


Key Accountabilities and Duties



  • Execute pre-formulation and formulation studies for small molecules and peptides (salt form screening, solubility screening in suitable buffers, co-solvents, pKa determination, excipient compatibility studies, stability studies for formulation selection, etc)

  • Perform formulation and process development studies for liquid and lyophilized parenteral drug products of small molecules and peptides (and as required of other biological molecules)

  • Carry out analytical methods and technologies to support formulation and process development (e.g. HPLC, content by UV, identity, color, clarity and opalescence, pH, osmolality, visible particles, subvisible particles, rheology).

  • Manufacture non-GMP drug product samples for supportive stability studies and preclinical use (e.g. GLP tox studies) applying aseptic working techniques

  • Maintain accurate and up to date records, including appropriate lab notebook recordings. Capable of achieving deliverables in a timely fashion

  • Install, qualify, and maintain equipment for formulation/process development, non-GMP manufacturing and analytics in close alignment with current best practices and regulations

  • Write and revise technical documents including lab SOPs and test protocols

  • Ensure safety and health protection following lab and safety instructions


Minimum Required Qualifications/Skills



  • Training on the job as lab technician or science/ engineering degree (BSc, MSc) in a relevant discipline, e.g. Pharmaceutical Sciences, Chemistry, Biochemistry

  • 1-3 years of experience as a research associate in the pharmaceutical industry, preferably in the area of pharmaceutical development of small molecule parenterals

  • Working experience in relevant pharmaceutical development and analytical technologies

  • Good reporting, interpretation and documentation of scientific results

  • Experience with MS-Office applications

  • Detail-oriented

  • Good communication skills and proactive attitude

  • Enthusiastic and open-minded individual

  • Willingness to learn and carry out new and complex tasks

  • Good knowledge of written and spoken English


 


 


Lonza.  The place to Go, Stay and Grow.

</div>

At Lonza, we invest in great people. We encourage our employees to challenge themselves and we offer an environment that fosters creativity and success. Headquartered in Basel, Switzerland, we operate production, R&D, and business sites around the world, including Europe, North America, and Asia. 


Our vision:


We strive to be the leading supplier using science and technology to improve the quality of life.


Our mission:


We work with passion, using advanced technologies, to transform life science into new possibilities for our customers.
 


Do you want to help us as we shape the future of this great organization?


 


Job Description Summary


For DPS (Drug Product Services) in Basel Switzerland, we have an open opportunity for a Research Associate. Working closely with Analytical and Formulation Development, this team offers specialized services solutions for customers. Become part of this exciting opportunity by applying for the position of Research Associate Formulation Development.


Key Accountabilities and Duties



  • Execute pre-formulation and formulation studies for small molecules and peptides (salt form screening, solubility screening in suitable buffers, co-solvents, pKa determination, excipient compatibility studies, stability studies for formulation selection, etc)

  • Perform formulation and process development studies for liquid and lyophilized parenteral drug products of small molecules and peptides (and as required of other biological molecules)

  • Carry out analytical methods and technologies to support formulation and process development (e.g. HPLC, content by UV, identity, color, clarity and opalescence, pH, osmolality, visible particles, subvisible particles, rheology).

  • Manufacture non-GMP drug product samples for supportive stability studies and preclinical use (e.g. GLP tox studies) applying aseptic working techniques

  • Maintain accurate and up to date records, including appropriate lab notebook recordings. Capable of achieving deliverables in a timely fashion

  • Install, qualify, and maintain equipment for formulation/process development, non-GMP manufacturing and analytics in close alignment with current best practices and regulations

  • Write and revise technical documents including lab SOPs and test protocols

  • Ensure safety and health protection following lab and safety instructions


Minimum Required Qualifications/Skills



  • Training on the job as lab technician or science/ engineering degree (BSc, MSc) in a relevant discipline, e.g. Pharmaceutical Sciences, Chemistry, Biochemistry

  • 1-3 years of experience as a research associate in the pharmaceutical industry, preferably in the area of pharmaceutical development of small molecule parenterals

  • Working experience in relevant pharmaceutical development and analytical technologies

  • Good reporting, interpretation and documentation of scientific results

  • Experience with MS-Office applications

  • Detail-oriented

  • Good communication skills and proactive attitude

  • Enthusiastic and open-minded individual

  • Willingness to learn and carry out new and complex tasks

  • Good knowledge of written and spoken English


 


 


Lonza.  The place to Go, Stay and Grow.

Details