High Density Perfused Batch Facility-DSP Production Engineer(80-100%*)
Inseriert am: 11.02.2021
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Job ID 311346BR Position Title High Density Perfused Batch Facility-DSP Production Engineer(80-100%*) Apply to Job
Job Description
1 fully operational commercial-scale TRD technical Facility, that will enable the development & implementation of Novartis’s novel technology which is a paradigm shift in biologics manufacturing processes. The DSP HDPB Facility Scientist is required to plan & perform scientific experiments (or pilot plant processes) for the preparation and timely delivery of drug substances/products, processes and procedures in collaboration within a multifunctional project team coordinated by a Project leader.
You responsibilities:
• Responsible for several steps in the Downstream Process (DSP) e.g. column packing, chromatography steps and filtrations.
• Meet quality, quantity and timelines in all assigned projects; Plan, organize, perform and document scientific experiments/plant activities and plan, perform and contribute to project related scientific/technical activities under minimal guidance and/or in collaboration with experienced team members (e.g. contribute to interpretation and report results); And seeks proactively for support and coaching from Project Leader, Scientific Expert or other team members during the whole process if necessary.
• Provide efficient and robust processes for the manufacture and/or specialized facilities e.g. working under aseptic conditions as an expert with adequate guidance; Utilize special tools/equipment and/or specialized facilities e.g., containment/sterile labs; Evaluate new lab equipment and contribute to maintenance of lab instruments and infrastructure/equipment and the support functions of the team including ordering and logistics; And keep record of and manage chemicals, intermediates, excipients and solvents within own area of responsibility.
• Provide raw data documentation, evaluation and results interpretation; Propose and provide input for the design of next experiments; Optimize existing methods (lab or plant) and develop more efficient ones. Generate lab procedures, reports and/or instructions and/or SOP’s; and actively transfer procedures/instructions to pilot plant or production, including troubleshooting, process steering controls etc.; Work according to appropriate SOPs, GMP, GLP, QM, HSE, ISEC & Novartis Guidelines.
• Collaborate with other team members to facilitate deliveries of DS and/or DP; Communicate and address problems, perform safety and literature searches under moderate guidance from more experienced team member; Actively participate in project teams/meetings/networks and actively contributes to team goals; Ensure all own activities are aligned with overall drug development process. Strategic and scientific contribution to Networks, target achievements according to network charter and annual objectives
Minimum requirements
What you’ll bring to the role:
• Technician with continuing education (EU), BS or MS in Biotechnology, Biochem./Chem. Eng., Biopharmaceutical Sciences or equivalent (Preferred)
• Fluent in site-language is an asset. Fluent in English (oral & written).
• Required DSP Biologics experience: Min 5 successful years as Production Engineer/Associate Scientist/Scientist or 3-4 years for BS or 2-3 years for MS
• Awareness/proven experience for safe handling of chemicals, potentially dangerous materials & equipment.
• Skills & Knowledge: Good scientific/technical knowledge in specific area (e.g. column packing, chromatography, filtration). Working GMP experience highly desirable (Biologics). Proficient with plant & technical tools (aseptic working techniques, working under GMP conditions). Good knowledge of software/computer tools (e.g. DeltaV or equivalent manufacturing execution systems). Good English presentation & scientific/technical writing skills. Good communication skills, strong team-working & collaboration skills
Why consider Novartis?
799 million. That’s how many lives our products touched in 2019. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?
We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.
Imagine what you could do at Novartis!
Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.
Join our Novartis Network:
If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: talentnetwork.novartis.com/network
*Some restrictions on flexible working options may apply and will be discussed during interview if applicable. Division Global Drug Development Business Unit TECHNICAL R & D GDD Location Switzerland Site Basel Company/Legal Entity Novartis Pharma AG Functional Area Research & Development Job Type Full Time Employment Type Regular Shift Work No
